Research Article

Different Tidal Volumes May Jeopardize Pulmonary Redox and Inflammatory Status in Healthy Rats Undergoing Mechanical Ventilation

Table 3

Biomarkers of oxidative stress in lung parenchyma of animals.

GroupCGMVG4MVG8MVG12

TBARS (nmol/mg protein)a,b,c
PTN CARB (nmol/mg protein)a,b
SOD (U/mg protein)a,b
CAT (U/mg protein)a
MPO (Um/mg protein)a

CG: control group; MVG4: mechanical ventilation group 4 mL/kg; MVG8: mechanical ventilation group 8 mL/kg; MVG12: mechanical ventilation group 12 mL/kg; TBARS: thiobarbituric acid reactive substances; PTN CARB: protein carbonyl; SOD: superoxide dismutase; CAT: catalase; MPO: myeloperoxidase. aRepresents a significant difference in relation to CG. bRepresents a significant difference in relation to MVG4. cRepresents a significant difference in relation to MVG8. Data are expressed as . Analysis of Variance One-Way ANOVA followed by Tukey’s posttest (). animals per group.