Metformin and tBHQ Treatment Combined with an Exercise Regime Prevents Osteosarcopenic Obesity in Middle-Aged Wistar Female Rats

Table 2

Biochemical parameters of HFD-treated groups.

	Treated groups (14 months of age)
	HFD SED	HFD SED + MTF	HFD SED + tBHQ	HFD SED + MTF + tBHQ	HFD + EX	HFD + EX + MTF + tBHQ
AST (U/L)
ALT (U/L)
GGT (U/L)
Cholesterol
HDL mg/dL
Tryglicerides mg/dL
Creatinine mg/dL
Glucose mg/dL

The table shows the mean and standard deviation of ALT, AST, GGT, cholesterol, HDL, triglycerides, creatinine, and glucose that were determined in HFD-rats and the respective treatments at 14 months of age. The significant statistical differences between groups with respect to the HFD are marked with . The exact probability value is indicated in the graph. The comparisons were established using ANOVA and a post hoc Holm-Sidak . .