Research Article

Comparative Studies on the Hepatoprotective Effect of White and Coloured Rice Bran Oil against Acetaminophen-Induced Oxidative Stress in Mice through Antioxidant- and Xenobiotic-Metabolizing Systems

Table 3

The alteration of some liver injury and oxidative stress markers in APAP-induced mice after administration of various RBOs.

TreatmentSerum ALT (U L–1)Hepatic MDA (nmol mg-1 protein)Hepatic total GSH (nmol mg-1 protein)GSSG/GSH ratio

Vehicle
WRBO
CRBO
APAP
APAP+WRBO
APAP+CRBO
APAP+NAC

Values are represented as (). Significantly different from a vehicle group (). #Significantly different from APAP group (). $Significantly different from APAP+NAC group (). ALT: alanine aminotransferase; MDA: malondialdehyde; APAP: acetaminophen; WRBO: white rice bran oil; CRBO: coloured rice bran oil; NAC: -acetylcysteine.