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Bacteriocins | Classification | Resource | Highlights |
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Nisin A | Lanthipeptide | L. lactis | Decreasing the levels of IL-6, IL-8, and TNF-α and reduce the growth of bacteria in the wound [73] |
Nisin Z | Lanthipeptide | L. lactis | Inhibiting S. agalactiae and S. aureus, alleviating mastitis in cows [74] |
Nisin | Lanthipeptide | L. lactis | Increasing the level of IL-12 in macrophages [82], adjust the levels of inflammatory factors in both directions and promote immune balance [83]. Decrease the levels of TNF-α, TNF-β, NF-κB, IL-1, and ROS in mice [153] |
Nisin P | Lanthipeptide | S. lactis SMN003 | Regulating cytokine concentration to reduce uterine inflammation in rats [75] |
Thiostrepton | Thiopeptide | Streptomyces sp. | Inhibiting psoriasis-like inflammation induced by TLR7, TLR8, and TLR9 [86] |
Microcin M | Microcin | E. coli MC4100 | Inhibiting intestinal pathogenic bacteria and reducing intestinal inflammation [77] |
Microcin J25 | Lasso peptide | E. coli | Improving intestinal inflammation of broiler and mouse caused by Salmonella and ETEC [78, 79] |
Sublancin | Glycocin | B. subtilis 800 | Enhancing macrophage function, increase CD 4+ and CD 8+ cells, thereby enhancing immune response [84, 85]. Inhibiting NF-κB, relieving intestinal inflammation [157] |
Gassericin A | Circular bacteriocins | L. gasseri LA39 | Binding to KRT19 thus promote fluid absorption and decrease secretion early-weaned piglets [158] |
Salivaricin LHM | Class II | L. salivarius | Inhibiting inflammation caused by P. aeruginosa, with immune regulation in mice [81] |
Plantaricin EF | Class IIb | L. plantarum | Reducing obesity and fat inflammation [76] |
Lmo2776 | Class IId | L. monocytogenes | Targeting the commensal P. copri and modulate intestinal infection in mice [159] |
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