Research Article
Immunotherapy Using Oxygenated Water and Tumor-Derived Exosomes Potentiates Antitumor Immune Response and Attenuates Malignancy Tendency in Mice Model of Breast Cancer
Figure 5
Impact of treatment with oxygenated water and/or exosome on tumor-promoting immune responses. Two markers of Treg and Th2 including FoxP3 and IL-4, respectively, were evaluated. Microscopic view of immunohistochemical staining of serial sections in spleen tissue sections using anti-FoxP3 and -IL-4 antibodies is shown (a, c). The percentage of each molecule in the spleen was analyzed (b, d). The data are shown as the .
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