Mitochondrial Dysfunction Contributes to Aging-Related Atrial Fibrillation

Figure 3

Telomere-associated molecules in AF patients. (a) p53 mRNA in AF patients was higher than controls and without statistical differences; (b, c) no significant differences of p53 mRNA among different types of AF and different age groups; (d) the expression of PGC-1α mRNA in leukocytes was significantly reduced in AF patients; (e) no significant differences of PGC-1α mRNA among different types of AF; (f) the expression of PGC-1α mRNA was significantly lower in AF patients in the long-living age group; (g) the serum PGC-1α concentration was significantly reduced in AF patients; (h) no significant differences of serum PGC-1α concentration among different types of AF; (i) the serum PGC-1α concentration was significantly reduced in AF patients in the elderly age group and senile age group. AF: atrial fibrillation.

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