Research Article

Mitochondrial Dysfunction Contributes to Aging-Related Atrial Fibrillation

Table 1

Clinical and biochemical characteristics of AF patients and controls.

CharacteristicThe controls ()AF patients () value

Clinical parameters
 Age (years)0.629
 Male, (%)96 (100)96 (100)1.000
 BMI (kg/m2)0.106
 Smoking, (%)16 (16.67)21 (21.88)0.363
 History of CHD, (%)21 (21.88)18 (18.75)0.593
 Hypertension, (%)42 (43.75)47 (48.96)0.472
 Diabetes mellitus, (%)15 (15.62)17 (17.71)0.700
 Hyperlipidemia24 (25.00)20 (20.83)0.495
 Antihypertensive medication, (%)42 (43.75)46 (47.92)0.565
 Glucose lowering treatment, (%)14 (14.58)15 (15.63)0.841
 Lipid-lowering medication, (%)41 (42.71)34 (35.42)0.303
 SBP (mmHg)0.382
 DBP (mmHg)0.109
Laboratory parameters
 TC (mmol/L)0.464
 TG (mmol/L)0.107
 LDL-C (mmol/L)0.236
 HDL-C (mmol/L)0.283
 Cr (mmol/L)0.077
 BUN (mmol/L)0.299
 UA (mmol/L)0.025
 FBG (mmol/L)0.829
 GHb (%)0.311
 CRP (mg/dL)0.077
Echocardiographic parameters
 LVEF (%)0.056
 LAD (mm)0.028

Abbreviations: BMI: body mass index; CHD: coronary heart disease; SBP: systolic blood pressure; DBP: diastolic blood pressure; TC: total cholesterol; TG: triglyceride; LDL-C: low-density lipoprotein cholesterol; HDL-C: high-density lipoprotein cholesterol; Cr: creatinine; BUN: blood urea nitrogen; UA: uric acid; FBG: fasting blood glucose; GHb: glycated hemoglobin; CRP: C-reactive protein; LVEF: left ventricular ejection fraction; LAD: left atrial diameter. with italic font means statistically significant.