Research Article

Mitochondrial Dysfunction Contributes to Aging-Related Atrial Fibrillation

Table 2

Clinical and biochemical characteristics of subjects without other diseases.

CharacteristicThe controls ()AF patients () value

Clinical parameters
 Age (years)0.530
 Male, (%)26 (100)23 (100)1.000
 BMI (kg/m2)0.684
 SBP (mmHg)0.289
 DBP (mmHg)0.874
Laboratory parameters
 TC (mmol/L)0.170
 TG (mmol/L)0.201
 LDL-C (mmol/L)0.078
 HDL-C (mmol/L)0.083
 Cr (mmol/L)0.145
 BUN (mmol/L)0.256
 UA (mmol/L)0.731
 FBG (mmol/L)0.518
 GHb (%)0.998
 CRP(mg/dL)0.011
Echocardiographic parameters
 LVEF (%)0.098
 LAD (mm)0.076
Telomere-associated molecules
 LTL ( ratio)<0.001
 Leukocyte p53 mRNA0.395
 Leukocyte PGC-1α mRNA0.004
 Serum PGC-1α (pg/mL)0.003

Abbreviations: BMI: body mass index; SBP: systolic blood pressure; DBP: diastolic blood pressure; TC: total cholesterol; TG: triglyceride; LDL-C: low-density lipoprotein cholesterol; HDL-C: high-density lipoprotein cholesterol; Cr: creatinine; BUN: blood urea nitrogen; UA: uric acid; FBG: fasting blood glucose; GHb: glycated hemoglobin; CRP: C-reactive protein; LVEF: left ventricular ejection fraction; LAD: left atrial diameter. with italic font means statistically significant.