A Novel Ruthenium-Fluvastatin Complex Downregulates SNCG Expression to Modulate Breast Carcinoma Cell Proliferation and Apoptosis via Activating the PI3K/Akt/mTOR/VEGF/MMP9 Pathway

Table 5

Serum biochemistry findings in male Swiss albino mice treated with the ruthenium-fluvastatin complex for a 28-day repeated-dose oral subacute toxicity test.

Parameters (±SEM)	Control	Ru-flu complex (200 mg)	Ru-flu complex (100 mg)	Ru-flu complex (50 mg)	Ru-flu complex (25 mg)
AST		^#
ALT		^#
ALP		^#
Total protein (g/dL)		^#
Blood urea nitrogen (mg/dL)		^#
Creatinine (mg/dL)
Glucose (mg/dL)		^#
Cholesterol (mg/dL)

. Results are analyzed by the -test and one-way ANOVA and confirmed by Dunnett’s multiple comparison test. ^#Significant difference at , when compared with the control.