Review Article
The Role of Mitochondrial Quality Control in Cardiac Ischemia/Reperfusion Injury
Table 1
Therapeutic application targeting MQC to attenuate IR injury.
| Therapies | Mechanisms | References |
| Dapagliflozin | Improve left ventricular function | Lahnwong et al., 2020 [122] | Melatonin | Improve PPARγ expression | Zhou et al., 2017 [123] | Istaroxime | Stimulate SERCA to dilate blood vessels and decrease ROS production | Hasenfuss et al., 2011 [125] | SS31-Mito | Enhance LVEF and energy integrity with higher PGC-1α and Cyt c | Lee et al., 2018 [127] |
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