Antioxidant Barrier and Oxidative Damage to Proteins, Lipids, and DNA/RNA in Adrenal Tumor Patients

Table 1

Clinical and laboratory characteristics of the controls, incidentaloma, pheochromocytoma, and Cushing’s/Conn’s adenoma patients. Results are presented as median with 25% and 75% percentiles. , , , and indicate significant differences from the controls; ^, ^^^^ indicates significant differences from the pheochromocytoma group; ~ indicates significant differences from Cushing’s/Conn’s adenoma group. BMI: body mass index; HGB: hemoglobin; PLT: platelet count; RBC: red blood cell count; WBC: white blood cell count.

	Controls ()	Incidentaloma ()	Pheochromocytoma ()	Cushig’s/Conn’s adenoma ()	ANOVA
Age	59 (50-65)	61 (54-65)	56 (50-65)	59 (53-65)
BMI (kg/m^2)	23.04 (22.6-23.82)	29.62 (26.13-34.98)	26.75 (22.58-31.97)	30.57 (27.1-32.5)
Glucose (mg/dl)	76 (72-82.25)	101 (89.5-113.5)	84.5 (79.25-104.3)	97.5 (82.5-110)
Na^+ (mmol/l)	139 (137-140)	140 (138-141)	139.5 (137-141)	138 (136-141)
K^+ (mmol/l)	4.39 (4.15-4.66)	4.51 (4.29-4.81)	4.28 (4.06-4.69)	4.32 (3.78-4.65)
WBC (10^3/μl)	7.5 (6.8-8.3)	7.04 (5.265-8.8)	7.51 (6.428-8.743)	7.27 (6.038-9.17)
RBC (10^6/μl)	4.6 (4.5-4.9)	4.74 (4.35-4.98)	4.51 (4.135-4.808)	4.625 (4.385-4.81)
HGB (g/dl)	13.8 (13.4-14.1)	14.2 (13.5-14.7)	14.1 (12.7-14.9)	14.1 (13.3-14.5)
PLT (10^3/μl)	289 (275-300)	225 (183.5-270.5)	264.5 (215-285.3)	195^ (165-237)
Serum cortisol before 10 a.m. (μg/dl)	11 (9.2-16)	15 (11-19)	15 (11-20)	12 (10-20)
Urine methanephrine (μg/24 h)	118 (87-208)	98^^^^ (78-176)	592 (425-862)	122.5^^^^ (94-223)
Urine normethanephrine (μg/24 h)	234 (173-308)	233^^^^^~ (174-331)	655 (553-934)	394^ (271-435)
Aldosterone (ng/dl)	12.3 (8.63-20.18)	12.08^~ (6.8-19.56)	16.3 (10.82-21.88)	18.56 (11.56-35.8)
Size of the tumor (cm)		4.2 (2.65-5.5)	3.8 (3.5-4.8)	3.45 (2.025-4.95)