Methionine Protects Mammary Cells against Oxidative Stress through Producing S-Adenosylmethionine to Maintain mTORC1 Signaling Activity

<div>Methionine improved cell viability and reduced autophagy under oxidative stress condition. (a) L-Methionine (Met) and its hydroxyl analogue DL-2-hydroxy-4-methylthiobutanoic acid (HMTBA) relived H<sub>2</sub>O<sub>2</sub>-induced reduction of cell viability. (b) Methionine alleviated H<sub>2</sub>O<sub>2</sub>-induced inhibition of mTORC1 signaling activity. 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Oxidative Medicine and Cellular Longevity

fig5

Figure 5

Figure 5: Methionine Protects Mammary Cells against Oxidative Stress through Producing S-Adenosylmethionine to Maintain mTORC1 Signaling Activity 