Research Article
Integrative Functional Genomic Analysis of Molecular Signatures and Mechanistic Pathways in the Cell Cycle Underlying Alzheimer’s Disease
Table 3
PCC and GS of signature trophic receptors.
| | Receptor | moduleColor | PCC.cellcycle | GS.AD | p.GS.AD |
| | GABRG2 | Turquoise | 0.419343809 | -0.4121841 | 4.61621E-14 | | PGRMC1 | Turquoise | 0.405662742 | -0.3663381 | 3.24182E-11 | | EPHA4 | Turquoise | 0.404438747 | -0.3652521 | 3.74087E-11 | | MAGED1 | Turquoise | 0.404022816 | -0.3860747 | 2.18463E-12 | | GRIA2 | Turquoise | 0.394280106 | -0.3667586 | 3.06654E-11 | | CHRM1 | Turquoise | 0.381313001 | -0.3271977 | 4.06247E-09 | | TNFRSF1B | Turquoise | 0.353972271 | 0.3201443 | 9.04973E-09 | | GRIN2A | Turquoise | 0.352962267 | -0.4108274 | 5.68839E-14 | | TNFRSF1A | Turquoise | 0.341193899 | 0.3440933 | 5.47841E-10 | | RXRA | Turquoise | 0.339039633 | 0.3940831 | 6.93657E-13 |
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AD: Alzheimer’s disease; GS: gene significance; PCC: Pearson correlation coefficient.
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