Exploring the Role and Mechanism of pAMPKα-Mediated Dysregulation of Brf1 and RNA Pol III Genes

Table 1

Correlation between Brf1 expression and clinicopathological features in 226 primary lung cancers.

Parameters	Low Brf1 expression	High Brf1 expression	Chi-squared test value	Fisher’s exact test value
	(39.4%)	(60.6%)
Age
<48	7 (7.9%)	6 (4.4%)
≥48	82 (92.1%)	131 (95.6%)	0.272	0.381
Gender
Male	53 (59.6%)	114 (83.2%)
Female	36 (40.4%)	23 (16.8%)	0.000	0.000
Differentiation status
Well/moderate	53 (59.6%)	77 (56.2%)
Poor and others	36 (40.4%)	60 (43.8%)	0.619	0.680
Lymph node invasion (N stage)
Absent	72 (80.9%)	91 (66.4%)
Present	17 (19.1%)	46 (33.6%)	0.018	0.022
Clinical stage
I, II	27 (30.3%)	75 (54.7%)
III, IV	62 (69.7%)	62 (45.3%)	0.000	0.000

values determined by using SPSS 20.0. All statistical tests were two-sided.