Downregulation of ATP6V1A Involved in Alzheimer’s Disease via Synaptic Vesicle Cycle, Phagosome, and Oxidative Phosphorylation

Figure 4

Module-pathway regulatory network and AUC analysis. Scatter diagram of module membership versus gene significance (a). Global regulatory network on DEGs interacting with ATP6V1A (b): red represents high expression; blue and yellow indicate low expression; the size of nodes reflects the degree of gene connectivity. Identification of cross-talking pathways of ATP6V1A (c): yellow indicates the low ATP6V1A expression. AUC analysis in AD prediction (d). AD: Alzheimer’s disease; AUC: area under the curve.

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