Research Article
The Combination Treatment of Curcumin and Probucol Protects Chondrocytes from TNF-α Induced Inflammation by Enhancing Autophagy and Reducing Apoptosis via the PI3K-Akt-mTOR Pathway
Figure 5
Probucol and curcumin inhibited OA by targeting the PI3K/Akt/mTOR pathway in chondrocytes. (a–f) Western blot results for quantitative analysis of PI3K, p-PI3K, Akt, p-Akt, mTOR, and p-mTOR protein expression in chondrocytes. The data are shown as the . & and indicate and 0.05 vs. OA, respectively. All experiments were carried out three times.
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