Using Genomic and Transcriptome Analyses to Identify the Role of the Oxidative Stress Pathway in Renal Clear Cell Carcinoma and Its Potential Therapeutic Significance

Figure 1

The results of gene expression derived from TCGA database. (a) Heatmap shows the level of the CNV gain mutations of the 32 genes in 32 types of cancer. The area and color of a circle show the level of gain mutation; the larger and closer the circle to a warm color, the higher its level. (b) Heatmap showing the level of the CNV loss mutations of the genes. The area and color of a circle show the level of loss mutation, the same as those in (a). (c) The PPI network diagram showing the interaction among the 32 oxidative stress- (OS-) related genes. (d) Heatmap showing the level of the SNV frequency of the genes; the color bar on the right side shows cool colors that indicate a lower level and warm colors that indicate a higher level of frequency.

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