Xinkeshu Improves Endothelial Function and Augments Reendothelialization Capacity in Coronary Artery Disease with Anxiety/Depression

Figure 4

XKS improves the in vitro functions and in vivo endothelial repair capacity of EPCs. (a) The representative photographs of migration function and (b) the mean value of migrated cell numbers of EPCs incubated among different concentrations of XKS ( and vs. the vehicle group, ). (c) The representative photographs of adhesion function and (d) the mean value of adhering cell numbers of EPCs incubated among different concentrations of XKS ( and vs. the vehicle group, ). (e) Representative photographs and quantification analyses of reendothelialization areas (white) of the injured carotid arteries in nude mice 3 days after carotid denudation surgery plus intravenous injection of EPCs ( cells) with or without XKS (vs. the non-XKS group, ). (f) The pathological changes of endothelium from carotid arteries in hematoxylin-eosin (HE) and immunohistochemistry (IHC) staining of CD31 (magnification: 400).

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