Bioactive Compounds of Raspberry Oil Emulsions Induced Oxidative Stress via Stimulating the Accumulation of Reactive Oxygen Species and NO in Cancer Cells

Table 3

values (concentration that causes 50% decrease in cell growth) of oil emulsions from raspberry oils extracted by supercritical CO₂ (ROSCO2) and cold pressed (ROCOP) against different cell lines determined with the SRB assay. The results are presented as mean (SD).

Cell line	values (%)		value
	ROSCO2	ROCOP
LoVo	15.0 (2.5)	23.1 (3.4)	0.0026
LoVo/DX	17.1 (2.2)	18.7 (3.0)	0.36
MCF7	69.4 (7.3)	35.5 (8.0)	0.0001
MCF7/DX	48.3 (2.2)	52.2 (2.8)	0.04
A549	14.5 (2.8)	14.4 (2.7)	0.96
NHDF	Nontoxic	57.0 (2.4)	N/A

LoVo: colon adenocarcinoma cell line; LoVo/DX: doxorubicin-resistant colon adenocarcinoma cell line; MCF7: breast cancer cell line; MCF7/DX: doxorubicin-resistant breast cancer cell line; A549: lung cancer cell line; NHDF: normal human dermal fibroblast; N/A: not applicable.