Vitamin E TPGS 1000 Induces Apoptosis in the K562 Cell Line: Implications for Chronic Myeloid Leukemia

Figure 4

TPGS induces oxidation of DJ-1 (at Cys106 residue) and activation of protein caspase-3 in K562. K562 cells were incubated with increasing concentrations of TPGS (10–80 μM) at 37°C for 24 h. (a) Representative contour plot figures showing the oxDJ-1⁺/caspase-3⁺ double-positive population (Q2). (b) Quantification of percentages of double-positive population cells shown in (a).

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