Review Article
The Role of Oxidative Stress in Hypertensive Disorders of Pregnancy (Preeclampsia, Gestational Hypertension) and Metabolic Disorder of Pregnancy (Gestational Diabetes Mellitus)
Figure 2
Schematic representation of “uncoupling” of nitric oxide (NO) synthesis, adapted from [70]. Suboptimal concentrations (↓) tetrahydrobiopterin (BH4) are required for “uncoupling.” Superoxide anion: O; hydrogen peroxide: H2O2; peroxynitrite anion: OONO−; endothelial NO synthase: eNOS.