Kirenol Inhibits B[a]P-Induced Oxidative Stress and Apoptosis in Endothelial Cells via Modulation of the Nrf2 Signaling Pathway

<div>Role of Nrf2 in KRL-induced HO-1 and NQO-1 expression in endothelial cells. (a) HUVECs cells were transfected transiently with siRNA-Nrf2 and treated with 25 <i>μ</i>mol KRL. Protein was isolated and analyzed for the measurement of Nrf2 protein by western blot analysis. (b) Western blot analysis to determine the levels of NQO-1 and HO-1.</div>

Oxidative Medicine and Cellular Longevity

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Figure 7

Figure 7: Kirenol Inhibits B[a]P-Induced Oxidative Stress and Apoptosis in Endothelial Cells via Modulation of the Nrf2 Signaling Pathway 