Stimulation of AMPK Prevents Diabetes-Induced Photoreceptor Cell Degeneration

Figure 3

AMPK stimulation prevented diabetes-induced photoreceptor cell degeneration through the regulation of mitochondrial function. The expression of PGC1α (a), Nrf1 (b), Tfam (c), and SOD2 (d) and the DNA copy number (g) in 661w cells treated with AGEs after AMPK stimulation were measured by qRT-PCR. (e, f) The effect of AMPK stimulation on the mitochondrial membrane potential in 661w cells after AGE treatment. The data are expressed as the ( for each group). , , .

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