Long-Term Administration of Abacavir and Etravirine Impairs Semen Quality and Alters Redox System and Bone Metabolism in Growing Male Wistar Rats

<table class="table-group" id="tab6"><tr><td><table class="table"><tr><td class="thead-hr" colspan="4"><hr/></td></tr><tr class="thead"><td class="align_left"></td><td class="align_center">Control group</td><td class="align_center">AB group</td><td class="align_center">ET group</td></tr><tr><td class="thead-hr" colspan="4"><hr/></td></tr><tr><td class="align_left">Tibial BMD [g/cm<sup>2</sup>]</td><td class="align_center">0.223 (0.220-0.234)</td><td class="align_center">0.228 (0.224-0.237)</td><td class="align_center">0.231 (0.226-0.234)</td></tr><tr><td class="align_left">Femoral BMD [g/cm<sup>2</sup>]</td><td class="align_center">0.276 (0.265-0.284)</td><td class="align_center">0.272 (0.265-0.279)</td><td class="align_center">0.276 (0.271-0.283)</td></tr><tr class="table-tr"><td colspan="4"><hr class="tbody-hr"/></td></tr></table></td></tr></table>

<div>Effect of 16-week administration of abacavir and etravirine on the bone mineral density (AB group: group receiving abacavir 60 mg/kg for 16 weeks; ET group: group receiving etravirine 40 mg/kg for 16 weeks. Results presented as median (lower quartile–upper quartile).</div>

Oxidative Medicine and Cellular Longevity

tab6

Table 6

Table 6: Long-Term Administration of Abacavir and Etravirine Impairs Semen Quality and Alters Redox System and Bone Metabolism in Growing Male Wistar Rats 

Table 6 | Long-Term Administration of Abacavir and Etravirine Impairs Semen Quality and Alters Redox System and Bone Metabolism in Growing Male Wistar Rats 