Research Article
THAP9-AS1 Promotes Tumorigenesis and Reduces ROS Generation through the JAK2/STAT3 Signaling Pathway by Increasing SOCS3 Promoter Methylation in Osteosarcoma
Figure 1
THAP9-AS1 was highly expressed in OS tissues and cells. (a) The expression of THAP9-AS1 was determined in OS cells. (b) The expression levels of THAP9-AS1 were significantly higher in OS tissues than in normal control tissues. (c) Patients with high expression of THAP9-AS1 (>mean) had relatively shorter survival times. (d) The results of the subcellular fractionation assay showed the nuclear expression of THAP9-AS1 in MG63 cells. (e) Subcellular localization (×200) of THAP9-AS1 in MG63 cells was detected by FISH. ; ; NT: nontumor tissues.
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