THAP9-AS1 Promotes Tumorigenesis and Reduces ROS Generation through the JAK2/STAT3 Signaling Pathway by Increasing SOCS3 Promoter Methylation in Osteosarcoma
Table 1
The correlations between clinicopathological features and dysregulation of moleculars.
Characteristics
No. of cases
THAP9-AS1
SOCS3 mRNA
Low,
High,
Low,
High,
Sex
0.379
0.707
Female
16
7
9
9
7
Male
24
14
10
12
12
Age (years)
0.988
0.528
<20
19
10
9
11
8
≥20
21
11
10
10
11
Histological type
0.877
0.398
Osteoblastic
29
15
14
14
15
Chondroblastic
11
6
5
7
4
Location
0.841
0.251
Femur
28
15
13
13
15
Tibia
12
6
6
8
4
TNM stage
0.028
<0.001
I, II
22
15
7
6
16
III
18
6
12
15
3
Tumor size (cm)
0.355
0.027
<5
20
12
8
7
13
≥5
20
9
11
14
6
Low: low expression (< mean); high: high expression (≥ mean); are present in italic.
