Research Article

Roles of the Immune/Methylation/Autophagy Landscape on Single-Cell Genotypes and Stroke Risk in Breast Cancer Microenvironment

Table 1

Demographics and clinicopathological characteristics of BRCA patients in the TCGA cohort in the high and low BCPRS groups.

VariableBRCA TCGA cohort
High BCPRS ()Low BCPRS () value

Survival state
 Alive434(92.93)457(97.86)
 Dead33(7.07)10(2.14)
 Follow-up time (day)0.002
 Age (year)0.216
T0.034
 T1118(25.27)125(26.77)
 T2266(56.96)284(60.81)
 T371(15.20)42(8.99)
 T412(2.57)14(3.00)
 NA0(0.00)2(0.43)
N0.007
 N0220(47.11)232(49.68)
 N1150(32.12)154(32.98)
 N245(9.64)58(12.42)
 N343(9.21)21(4.50)
 NA9(1.93)2(0.43)
M0.007
 M0371(79.44)406(86.94)
 M16(1.28)6(1.28)
 NA90(19.27)55(11.78)
Stage0.699
 Stage I76(16.27)83(17.77)
 Stage II268(57.39)276(59.10)
 Stage III111(23.77)96(20.56)
 Stage IV6(1.28)4(0.86)
 Stage X6(1.28)8(1.71)
Race0.151
 Asian33(7.07)23(4.93)
 Black or African American86(18.42)67(14.35)
 White305(65.31)331(70.88)
 NA43(9.21)46(9.85)
Treatment0.556
 Pharmaceutical225(48.18)234(50.11)
 Radiation242(51.82)233(49.89)
Immunity groups0.001
 High immunity group131(28.05)110(23.55)
 Medium immunity group285(61.03)267(57.17)
 Low immunity group51(10.92)90(19.27)
 StromalScore
 ImmuneScore
 ESTIMATEScore
 TumorPurity
 mRNAsi
 EREG.mRNAsi0.126
Relative expression of BCRRS-related genes
 HEY1
 IFNA13
 NKX2.3
 NR2F1
 POU5F1
 YY1

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