Microglia Polarization from M1 toward M2 Phenotype Is Promoted by <i>Astragalus Polysaccharides</i> Mediated through Inhibition of miR-155 in Experimental Autoimmune Encephalomyelitis

<div>APS inhibited LPS-induced microglia activation. Morphological changes of microglia in each group (a). The expression of the IBA1 protein was detected by immunofluorescence staining and western blot in each group (b, c). 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11 82 -12 113 -12Z"></path></g><g transform="matrix(.013,0,0,-0.013,43.785,0)"><path d="M241 635C89 635 35 457 35 312C35 153 89 -12 240 -12C390 -12 443 166 443 312C443 466 390 635 241 635ZM238 602C329 602 354 454 354 312C354 172 330 22 240 22C152 22 124 173 124 313S148 602 238 602Z"></path></g><g transform="matrix(.013,0,0,-0.013,50.025,0)"><path d="M384 0V27C293 34 287 42 287 114V635C232 613 172 594 109 583V559L157 557C201 555 205 550 205 499V114C205 42 199 34 109 27V0H384Z"></path></g></svg>.</span> Compared with the EAE group, #<span class="nowrap"><svg height="9.2729pt" id="M68" style="vertical-align:-0.6370001pt" version="1.1" viewbox="-0.0498162 -8.6359 44.8393 9.2729" width="44.8393pt" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink"><g transform="matrix(.013,0,0,-0.013,0,0)"><path d="M600 480C600 590 528 650 384 650H143L137 622C222 614 225 607 210 531L130 127C113 41 106 36 23 28L17 0H294L300 28C204 36 195 42 212 127L243 284L314 263C327 263 339 263 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Oxidative Medicine and Cellular Longevity

fig2

Figure 2

Figure 2: Microglia Polarization from M1 toward M2 Phenotype Is Promoted by <i>Astragalus Polysaccharides</i> Mediated through Inhibition of miR-155 in Experimental Autoimmune Encephalomyelitis 

Figure 2 | Microglia Polarization from M1 toward M2 Phenotype Is Promoted by Astragalus Polysaccharides Mediated through Inhibition of miR-155 in Experimental Autoimmune Encephalomyelitis 