Microglia Polarization from M1 toward M2 Phenotype Is Promoted by Astragalus Polysaccharides Mediated through Inhibition of miR-155 in Experimental Autoimmune Encephalomyelitis

Figure 3

APS promoted the phenotypic polarization from M1 to M2 of microglia in vitro. Relative mRNA expression levels of M1 polarization markers (TNF-α, iNOS, IL-12) and M2 polarization markers (Arg-1, IL-10, CD206) were detected by qRT-PCR (a–f). The protein expression of M1 polarization marker (iNOS) and M2 polarization marker (Arg-1) was detected by western blot (g). Compared with the CON group, , . Compared with the EAE group, #, ##.

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