SPP1 Promotes Enzalutamide Resistance and Epithelial-Mesenchymal-Transition Activation in Castration-Resistant Prostate Cancer via PI3K/AKT and ERK1/2 Pathways

Figure 8

The single-gene GSEA of SPP1 and gene correlation analysis based on TCGA datamining. (a, b) SPP1 could significantly regulated EMT and MAPK pathway in the high-expression group. (c, d) Expression of MAPK1 and MAPK 14 was positively associated with that of SPP1 significantly.

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