Review Article

[Retracted] ROS Signaling-Mediated Novel Biological Targets: Brf1 and RNA Pol III Genes

Figure 2

Alcohol-activated JNK1 mediates ERα and Runx2. Alcohol induces JNK1 activation to increase the expression of ERα and Runx2, resulting in deregulation of Pol III genes to promote breast cancer development. Blue P: phosphorylation group.