Intra-articular Injection of Baicalein Inhibits Cartilage Catabolism and NLRP3 Inflammasome Signaling in a Posttraumatic OA Model

Figure 1

Comparisons of gross appearance of femoral condyle and tibial plateau in rat DMM osteoarthritis models and different doses of baicalein- or DXM-treated rats at 7 weeks postsurgery. The condyle of the distal femur showed a rough joint surface at the intercondylar space and osteochondral defect (black box). The medial tibial plateau (MTP) exhibited osteophyte formation (blue arrows) ().