Role of Exosomal MicroRNAs and Their Crosstalk with Oxidative Stress in the Pathogenesis of Osteoporosis

Table 1

The role of exosomal miRNAs in osteoporosis.

Exosome source	RNA extraction	RNA identification	Exosomal miRNA(s)	Regulatory role	Reference
Human bone marrow mesenchymal stem cells	Exosome extraction kits (QIAGEN, Germany)	RT-qPCR	miR-186	Ameliorate	Li et al., 2021, [81]
Human umbilical cord mesenchymal stem cell	Trizol reagent	RT-qPCR	miR-1263	Ameliorate	Yang et al., 2020, [80]
Vascular endothelial cell	Trizol reagent	RT-PCR	miR-155	Ameliorate	Song et al. 2019, [79]
Bone marrow stromal cells of aging mice	Trizol reagent	RT-qPCR	miR-31a-5p	Aggravate	Xu et al., 2017, [78]
Bone marrow mesenchymal stem cells	Trizol reagent	RT-qPCR	miR-29a	Ameliorate	Lu et al., 2020