Role of IL-37- and IL-37-Treated Dendritic Cells in Acute Coronary Syndrome

Figure 2

Protective role of tDCs in MI. In heart, adoptive transfer of tDCs inhibited cardiac fibrosis, decreased inflammatory cells infiltration, and prevented left ventricular function following MI. In spleen, adoptive transfer of tDCs increased the number of Tregs and decreased Th1 and Th17 cells. TDCs: tolerogenic dendritic cells induced by troponin I plus interleukin-37; MI: myocardial infarction; Tregs: regulatory T cells.