System Analysis of ROS-Related Genes in the Prognosis, Immune Infiltration, and Drug Sensitivity in Hepatocellular Carcinoma

Figure 16

The expression and biological behavior of STK25 in liver cancer. (a) The level of STK25 expression was confirmed by GEO. (b) The protein level of STK25 expression was verified by IHC in liver cancer. Magnification, ×200. Scale bar: 50 μm. (c) STK25 knockdown inhibited the proliferation capacity of HepG2 cells and SMMC-7721 via CCK8 assays. (d) STK25 knockdown suppressed the proliferation capacity of HepG2 cells via EdU assays. Magnification, ×200. Scale bar: 50 μm. (e) STK25 knockdown suppressed the migration capacity of HepG2 cells via wound healing assays. Magnification, ×40. Scale bar: 200 μm. (f) STK25 knockdown suppressed the migration capacity of SMMC-7721 cells via wound healing assays. Magnification, ×40. Scale bar: 200 μm. (g) STK25 knockdown decreased the invasion capacity of liver cancer cells (HepG2 and SMMC-7721) via transwell invasive assays. Magnification, ×200. Scale bar: 50 μm. (h) STK25 knockdown decreased the migration capacity of liver cancer cells (HepG2 and SMMC-7721) via transwell migration assays. Magnification, ×200. Scale bar: 50 μm. (i) STK25 knockdown increased the apoptosis of HepG2 cells. (j) STK25 knockdown promoted the apoptosis of SMMC-7721 cells.

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