Furazolidone Increases Survival of Mice Exposed to Lethal Total Body Irradiation through the Antiapoptosis and Antiautophagy Mechanism

Figure 4

FZD treatment reduced apoptosis and autophagy in villi. (a) TUNEL staining of intestinal tissue sections. (b) The calculated statistical data from TUNEL staining. (c) Western blot analysis of apoptosis in intestinal tissue. Cleaved caspase-3, Bcl-2, PARP, p53, and H2AX were included. (d) Western blot analysis of autophagy in intestinal tissue of mice. MAPLC3, beclin-1, and ATG5 were included. Error bars are ( independent repeats), and values were calculated using two-tailed unpaired Student’s -test.

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