Salidroside Suppresses the Proliferation and Migration of Human Lung Cancer Cells through AMPK-Dependent NLRP3 Inflammasome Regulation

Figure 4

Coincubation with IL-1β abolishes the effects of salidroside (SAL) on cell proliferation and migration in LPS-exposed A549 cells. A549 cells were exposed to 10 μg/ml LPS in the presence of SAL (40 μM) and/or IL-1β (15 ng/ml) for 48 h. Cell viabilities were then measured using CCK-8 assays (a). After A549 cells were treated as described for 24 h (b) or 48 h (c), cell migration was determined through wound healing assays. . and vs. no LPS treatment; ^# and ^## vs. cells treated with LPS alone; ^& and ^&& vs. cells treated with LPS plus SAL. Values are ().

(a)

(b)

(c)