Salidroside Suppresses the Proliferation and Migration of Human Lung Cancer Cells through AMPK-Dependent NLRP3 Inflammasome Regulation

Figure 6

Influence of AMPK inhibition on the salidroside- (SAL-) mediated suppression of proliferation and migration in LPS-treated A549 cells. A549 cells were exposed to 10 μg/ml LPS in the presence of 40 μM SAL or 2 μM Compound C for 48 h. Cell viabilities were then measured using CCK-8 assays (a). After A549 cells were treated as described for 24 h (b) or 48 h (c), cell migration was determined through wound healing assays. . and vs. treatment without LPS; ^# and ^## vs. treatment with LPS alone; ^& and ^&& vs. treatment with LPS plus SAL. Values are ().

(a)

(b)

(c)