Predicting Severity and Intrahospital Mortality in COVID-19: The Place and Role of Oxidative Stress

Table 7

Linear regression analysis of candidate predictors for dependent variable—severity of COVID-19 infection (mild, moderate, or severe form of SARS-CoV-2 infection).

	Dependent variable: severity of COVID-19 infection
	Unstandardized coefficients ()	Std. error	Standardized coefficients (beta)
Age	0.007	0.006	0.133	1.111	0.270
Male gender	−0.022	0.146	−0.014	−0.152	0.879
Present HTA	0.322	0.124	0.225	2.598	0.011
Elevated body temperature	0.310	0.186	0.144	1.662	0.099
Anosmia	−1.621	0.696	−0.811	−2.328	0.022
Ageusia	1.601	0.712	0.783	2.247	0.026
Cough	−0.015	0.160	−0.010	−0.096	0.924
Dyspnea	0.101	0.141	0.070	0.714	0.477
RR	0.005	0.026	0.023	0.178	0.859
HR	0.012	0.010	0.143	1.172	0.245
SBP	0.008	0.009	0.148	0.845	0.401
DBP	0.006	0.016	0.065	0.370	0.712
PaO2	0.001	0.003	0.042	0.365	0.716
WBC	0.447	0.251	1.040	1.781	0.217
O2-	0.087	0.012	0.565	7.330	≤0.001
H2O2	−0.069	0.098	−0.056	−0.700	0.485
TBARS	−0.055	0.118	−0.045	−0.464	0.644
NO-	−0.087	0.093	−0.074	−0.932	0.353
CAT	0.175	0.098	0.141	1.780	0.078
Hospital (days)	−0.098	0.084	−0.641	−1.163	0.365
ICU (days)	0.025	0.013	0.191	1.989	0.049

RR: respiratory rate; HR: heart rate; SBP: systolic blood pressure; DBP: diastolic blood pressure; WBC: white blood cells; O₂⁻: superoxide anion radical; H₂O₂: hydrogen peroxide; CAT: catalase; ICU: intensive care unit.