Research Article

Anti-Interleukin-16 Neutralizing Antibody Treatment Alleviates Sepsis-Induced Cardiac Injury and Dysfunction via the Nuclear Factor Erythroid-2 Related Factor 2 Pathway in Mice

Figure 1

Establishment and pretreatment of the mouse sepsis model. WT: wild-type; PBS: phosphate-buffered saline; SOD: superoxide dismutase; LPS: lipopolysaccharide; CLP: cecal ligation and puncture; nAb: anti-IL-16 neutralizing antibody; CPU: CPUY192018; DMSO: dimethyl sulfoxide.