Review Article
The Role of Mitophagy in Regulating Cell Death
Table 1
The subcellular localization of the mitophagy-related protein.
| Protein | Subcellular localization | References |
| PINK1 | (1) Mitochondria (main): the inner and outer mitochondrial membrane (2) Cytosol (3) Endoplasmic reticulum | ([87]; [88]; [89]; [90]) | Parkin | (1) Cytosol (main) (2) Dysfunctional mitochondria (3) Endoplasmic reticulum (4) Golgi apparatus | [88] [29] [91] [92] | NIX/BNIP3L | (1) Mitochondria: the outer mitochondrial membrane (2) Endoplasmic reticulum | [51, 93] [66] | BNIP3 | (1) Mitochondria: the outer mitochondrial membrane (2) Endoplasmic reticulum | [51] [94] | FUNDC1 | (1) Mitochondria: the outer mitochondrial membrane | [75] |
|
|
Note: PINK1: PTEN-induced putative kinase 1; FUNDC1: Fun14 domain-containing protein 1; BNIP3L: BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like; BNIP3: BCL2-interacting protein 3.
|