Metabolomics Analysis of the Development of Sepsis and Potential Biomarkers of Sepsis-Induced Acute Kidney Injury

Table 2

Differential metabolic pathways (LPS2 vs. LPS6). The results of enriched compounds after screening and metabolic pathway enrichment analysis (MPEA) between the LPS2 and LPS6 groups are summarized in this table.

	Total in pathway	Expected	Hits	Raw P		Holm P	FDR	Impact	Enriched compounds
Biosynthesis of unsaturated fatty acids	42	0.95863	4	0.013612	4.2968	1	1	0	Arachidonic acid; Linoleic acid; Palmitic acid; Stearic acid
Histidine metabolism	15	0.34237	2	0.044048	3.1225	1	1	0.23077	1-Methylhistidine; L-Histidine

Holm: Holm-Bonferroni method; FDR: false discovery rate.