Research Article
Protective Effects and Mechanisms of Recombinant Human Glutathione Peroxidase 4 on Isoproterenol-Induced Myocardial Ischemia Injury
Figure 7
rhGPx4 inhibits cardiomyocyte apoptosis in the heart tissue. (a) Representative images of TUNEL staining of the heart tissue (optical microscope, ×400). The apoptotic cardiomyocyte nucleus appears brown, and normal nuclei appear blue. (b) Ratio of TUNEL-positive cells (%). (c) Representative western blot bands of Bcl-2, Bax, Cleaved caspase-3, and β-actin. (d) The ratio of the Bcl-2/Bax expression in the heart tissue. (e) The expression levels of cleaved caspase-3 in the heart tissue. Data represent the (). ##, ### vs. control; vs. ISO.
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