HIF-1 Inhibitor YC-1 Reverses the Acquired Resistance of EGFR-Mutant HCC827 Cell Line with MET Amplification to Gefitinib

<div>Comparison of gefitinib sensitivity among HCC827 cells, HCC827 GR cells, HCC827 cells treated with YC-1, and HCC827 GR cells treated with YC-1. Cell viability was measured by MTT assay. The concentration of YC-1 was 40 <i>μ</i>M. 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Oxidative Medicine and Cellular Longevity

fig6

Figure 6

Figure 6: HIF-1 Inhibitor YC-1 Reverses the Acquired Resistance of EGFR-Mutant HCC827 Cell Line with MET Amplification to Gefitinib 