Low-Dose Copper Exposure Exacerbates Depression-Like Behavior in ApoE4 Transgenic Mice

<div>Low-dose copper exposure increased the number of astrocytes and microglia. Immunoreactivity of astroglia (GFAP) and microglia (Iba1) in the CA1 of the hippocampus. (a–c) The representative image of positive staining of GFAP (astrocytes) and Iba1 (microglia) in the CA1 hippocampus and quantitative analysis. The scale: 100 <i>μ</i>m and 50 <i>μ</i>m. 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Oxidative Medicine and Cellular Longevity

fig8

Figure 8

Figure 8: Low-Dose Copper Exposure Exacerbates Depression-Like Behavior in ApoE4 Transgenic Mice 