Circular RNAs: Novel Players in the Oxidative Stress-Mediated Pathologies, Biomarkers, and Therapeutic Targets

Table 2

The role of circRNAs in OxS in kidney diseases.

Cause	circRNA	Mediator	Mechanism	Role	Ref
Diabetes	circLRP6	miR-205; LTR4/NF-κB	Mediates the effect of ROS on mesangial cells	Pathogenic	[72]
Hypertension	circNr1h4	miR-155-5P; Far1	Prompts ROS synthesis	Pathogenic	[73]
Drug-induced	circ_0114427	miR-494; ATF3	Mediates the effect of ROS	Pathogenic	[74]
Sepsis	circVMA21	miR-9-3P; SMG1 protein	Alleviates OxS mediated inflammation and apoptosis	Protective	[75]