[Retracted] Oral Administration of Gintonin Protects the Brains of Mice against Aβ-Induced Alzheimer Disease Pathology: Antioxidant and Anti-Inflammatory Effects

Figure 3

Effects of gintonin against AD-like pathological changes in the mouse brains and in vitro cells: (a) immunofluorescence analysis of Aβ in the cortex and hippocampus of the experimental mice; (b) western blot analyses of APP, ADAM-10, BACE-1, and Aβ expression in the saline, Aβ, Aβ+gintonin, and gintonin-alone treatment groups; (c) western blot results for Aβ expression in HT-22 cells, with bar graphs indicating the expression levels; (d) immunofluorescence analysis of Aβ in different mouse groups and the respective graphs. A significant difference between Aβ and saline-treated groups; ^#a significant difference from Aβ+Gt-treated mice. The data are presented as the mean (SD) of three experiments. ^#; ; , . Gt: gintonin; Aβ: amyloid-beta; n: not significant.

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