Research Article
RIPK3 Induces Cardiomyocyte Necroptosis via Inhibition of AMPK-Parkin-Mitophagy in Cardiac Remodelling after Myocardial Infarction
Figure 3
RIPK3 initiated necroptosis via promoting mPTP opening (). (a–c) The expression change of PGAM5 and p-MLKL was determined by western blot in vitro. (d) The change of mPTP opening time. (e) The cardiomyocyte necroptosis was measured flow cytometry with Annexin V/PI staining. Necroptosis group: the percentage of PI+ cells. Data are shown as the , .
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