Research Article
Mitochondrial-Targeting Antioxidant SS-31 Suppresses Airway Inflammation and Oxidative Stress Induced by Cigarette Smoke
Figure 3
SS-31 attenuates CS-induced airway mucus hypersecretion. (a–d) Mouse lung tissue from control () (a), CS () (b), SS-31 (L)+CS () (c), and SS-31 (H)+CS () (d) groups after AB/PAS staining (400x magnification, scale ). (e) The positive percentage of epithelial area with AB/PAS staining. Bottom images depict enlarged views of boxed areas in corresponding top images. vs. control; # vs. CS. Abbreviations: AB/PAS: Alcian blue/periodic acid Schiff; CS: cigarette smoke; SS-31 (H): high-dose SS-31 (5 mg/kg); SS-31 (L): low-dose SS-31 (2.5 mg/kg).
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