Effects of Lipid Peroxidation-Mediated Ferroptosis on Severe Acute Pancreatitis-Induced Intestinal Barrier Injury and Bacterial Translocation

Figure 1

Serum biochemical indicators and intestinal histological changes at different time points. The activities of serum AMY (a) and LIPA (b) and the levels of TNF-α (c), IL-6 (d), DAO (e), and endotoxin (f) in the SAP group were significantly higher than those in the SO group. And the levels of AMY (a), LIPA (b), TNF-α (c), IL-6 (d), DAO (e), and endotoxin (f) in the group at 24 h were significantly lower than those in the SAP group. Representative ileum H&E-stained sections were obtained (g) (original magnification, ×200). These values are expressed as the (). The variables between groups were compared by Student’s -test and one-way ANOVA. and vs. the SO group; and vs. the SAP group.

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